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Marker chromosomes in parents to children with Down's syndrome

✍ Scribed by G. Annerén; J. Wahlström; N. Tommerup

Book ID
119839544
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
595 KB
Volume
25
Category
Article
ISSN
0009-9163

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Parental origin of chromosomes in Down's
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The number of 21 chromosomes of 15 individuals with Down's syndrome and their parents were examined in an attempt to determine the parental origin of the extra number 21 chromosome and the stage of meiosis at which nondisjunction occurred. Chromosomes were stained with quinacrine hydrochloride and p

Parental origin of the extra chromosome
Parental origin of the extra chromosome in Down's syndrome
✍ R. E. Magenis; K. M. Overton; J. Chamberlin; T. Brady; E. Lovrien 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 545 KB

Chromosome 21 fluorescent heteromorphisms were studied in 42 patients with Down's syndrome, their parents and their siblings. Included in this number are two instances of an aunt and niece affected with trisomy 21, and one of affected siblings. One case has a de novo 21/21 translocation. Blood group