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Rat and human plasma protein binding of die main metabolite of triflusal

โœ Scribed by J. Ramis; R. Mis; L. Conte; J. Forn

Book ID
115884043
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
226 KB
Volume
183
Category
Article
ISSN
0014-2999

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2-hydroxy-4-trifluoromethylbenzoic acid (HTB) is the main active metabolite of the platelet antiaggregant drug triflusal. Its binding to plasma proteins of rats and healthy volunteers in vitro and in vivo has been studied. Rats were given a single oral dose of 50 mg.kg-1 triflusal and the healthy vo

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