The purpose of this study was to determine the proportion of fetal nucleated red blood cells (NRBCs) among enriched NRBCs and to evaluate the effectiveness of enriching NRBCs in maternal blood using fluorescenceactivated cell sorting (FACS) to separate NRBCs. The origin of enriched NRBCs was determi
Rare-event analysis methods for detection of fetal red blood cells in maternal blood
โ Scribed by James E. Cupp; Dr. James F. Leary; Elsa Cernichiari; James C. S. Wood; Richard A. Doherty
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 722 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Prenatal diagnosis is presently performed following invasive procedures with variable risks of fetal loss; non-invasive procedures using fetal cells in maternal blood would be welcome for the early detection of fetal sex or aneuploidy. We describe a simple and rapid protocol to detect fetal cells an
Three major methods have been described for the isolation of fetal cells from maternal blood: fluorescenceactivated cell sorting (FACS), immunomagnetic beads, and magnetic-activated cell sorting (MACS). To date, no study has directly compared fetal cell recovery using each of these methods. Here we