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Rapid Self-assembly of α-Synuclein Observed by In Situ Atomic Force Microscopy

✍ Scribed by Wolfgang Hoyer; Dmitry Cherny; Vinod Subramaniam; Thomas M. Jovin


Book ID
116661315
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
761 KB
Volume
340
Category
Article
ISSN
0022-2836

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In this report, we applied in situ atomic force microscopy (AFM) to study the dynamic process of disassembly-assembly of a-synuclein (a-Syn) fibrils in different solutions. Most of the mica-adsorbed a-Syn fibrils disassemble into small particles step-by-step on the mica surface in diluted solutions,