## Abstract An improved method for the preparation of Merrifield resin esters is presented. This method is rapid, is free of racemization, and is not complicated by a quaternization side reaction. Chloromethylated resin beads, __t__โbutoxycarbonyl amino acid, and potassium __t__โbutoxide are heated
Rapid methods for the synthesis of peptides
โ Scribed by A. Loffet
- Publisher
- Elsevier Science
- Year
- 1994
- Weight
- 366 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0923-1137
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โฆ Synopsis
Rapid methods for the synthesis of peptides have been reviewed. This includes Merrifield solid-phase synthesis, Patchornik polymeric reagents as well as solution methods like Bodanszky's repetitive excess mixed anhydride and methane N-carboxyanhydride methods.
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