Rapid in vitro stimulation of parathyroid hypertensive factor secretion by 1,25-dihydroxyvitamin D3
β Scribed by S.K Sutherland; R.Z Lewanczuk; C.G Benishin
- Book ID
- 117599563
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 186 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0895-7061
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## Abstract Parathyroid hypertensive factor (PHF) is a novel substance secreted by the parathyroid gland (PTG), which is elevated in 30β40% of all hypertensive patients; specifically, the lowβrenin subset. However, very little is known about the regulation of PHF secretion. Since the classical para
Cultured microglial cells were examined for their ability to metabolize 25-hydroxyvitamin D, (25-(OH) D,). Upon exposure to lipopolysaccharide, microglial cells produced a vitamin D metabolite which comigrated with synthetic 1,25-dihydroxyvitamin D, (1,25-(OH),D,) in two different systems of high pe