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Rapid characterization of somatic cell hybrids using fluorescent in situ hybridization

โœ Scribed by N. Van Roy; G. Laureys; F. Speleman; G. Opdenakker; J.G. Leroy; U. Francke

Book ID
119105049
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
112 KB
Volume
56
Category
Article
ISSN
0165-4608

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In situ hybridization of hamsterlhuman hybrids with biotinylated human genomic D N A has revealed that human chromosomal DNA can integrate into the hamster genome and is not always cytologically detectable. This finding helps t o explain why discordancy can arise in gene mapping by failing to recogn