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Rapid and sensitive method for the determination of albendazole and albendazole sulphoxide in biological fluids

✍ Scribed by Paula E. Hoaksey; Kwablah Awadzi; Stephen A. Ward; Paul A. Coventry; Michael L'E. Orme; Geoffrey Edwards

Publisher
Elsevier Science
Year
1991
Weight
336 KB
Volume
566
Category
Article
ISSN
0378-4347

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## ABSTRACT The development and validation of an LC‐MS/MS method for the simultaneous determination of albendazole metabolites (albendazole sulfoxide and albendazole sulfone) in human plasma are described. Samples of 200 μL were extracted with ether–dichloromethane–chloroform (60:30:10, v/v/v). The