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Raman Spectroscopic Study of the Conformation and Melting of Poly(dG) · Poly(dC) and Poly(dG-dC) · Poly(dG-dC) in Aqueous Solution

✍ Scribed by Virginie Carrier; Rodrigue Savoie


Book ID
110220466
Publisher
Springer US
Year
2000
Tongue
English
Weight
318 KB
Volume
29
Category
Article
ISSN
0095-9782

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📜 SIMILAR VOLUMES


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## Abstract We have measured the ultraviolet circular dichroism spectra of oligo d(pG)~5~, poly dN AcG, poly dI, poly dC, two samples of poly dG, and four samples containing double‐stranded poly dG:dC. We find that oligo d(pG)~5~ and poly dG exist in self‐complexed forms as well as in single‐strand

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## Abstract The double‐stranded helical complexes of poly(dG‐dC) and of poly(dG‐m^5^dC) are shown to convert from B‐ to Z‐DNA‐type conformations at moderate or low ionic strengths, lower for the 5‐methyl than for the non‐methyl species, in a highly cooperative temperature‐dependent equilibrium. In