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Changes in the helical repeat of poly(dG-m5 dC) · poly(dG-m5dC) and poly(dG-dC) · poly(dG-dC) associated with the B—Z transition

✍ Scribed by Behe, M.; Zimmerman, S.; Felsenfeld, G.

Book ID
109724109
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
540 KB
Volume
293
Category
Article
ISSN
0028-0836

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Temperature-dependent conformational tra
Temperature-dependent conformational transitions in poly(dG-dC) and poly(dG-m5dC)
✍ Michael J. Behe; Gary Felsenfeld; Shousun Chen Szu; Elliot Charney 📂 Article 📅 1985 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 612 KB

## Abstract The double‐stranded helical complexes of poly(dG‐dC) and of poly(dG‐m^5^dC) are shown to convert from B‐ to Z‐DNA‐type conformations at moderate or low ionic strengths, lower for the 5‐methyl than for the non‐methyl species, in a highly cooperative temperature‐dependent equilibrium. In

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## Synopsis The vacuum CD spectra of poly(rGdC).poly(rGdC) and poly(dG-m 5dC).poly(dG-m5dC) have been obtained for the low-salt Zconformations of both polymers. The spectra are very similar to those for the high-salt Zforms. This behavior is consistent with the suggestion that the lowand high-salt

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✍ X. M. Hua; E. W. Prohofsky 📂 Article 📅 1988 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 448 KB

Normal modes of methylated Z-DNA poly(dG-m5dC) . (dG-m5dC) are computed by helix-lattice dynamics. Good agreement with Raman spectral data is obtained. We discuss improvements in the formulation of the problem that allow us to greatly reduce the size of the matrix used. This leads to greatly reduced