𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Radioresistant tumor cell lines derived from head and neck radiation failures

✍ Scribed by Dr. Ralph R. Weichselbaum; Michael A. Beckett; Srinivasan Vijayakumar; Susan Ahmed-Swan; Anatoly Dritschilo; Jeffrey L Schwartz; William J. Moran; Michael E. Goldman; Allen G. Tybor; Everett E. Vokes; William R. Panje

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
465 KB
Volume
11
Category
Article
ISSN
1043-3074

No coin nor oath required. For personal study only.

✦ Synopsis

We studied the in vitro radiobiological parameters of 16 human head and neck squamous cell carcinoma tumor cell lines cultured from patients who suffered local failure after a curative course of radiotherapy. The radiobiological parameters determined included Do, n, and 6. When compared with in vitro radiobiological parameters of tumor cells cultured from head and neck cancer patients prior to radiotherapy, human sarcoma cell lines, and normal human diploid fibroblasts studied in our laboratory (as well as other human tumor cell lines reported in the literature), tumor cells derived from radiotherapy failures on average are resistant to the cytotoxic effects of ionizing radiation.

πŸ“œ SIMILAR VOLUMES

Elevated furin expression in aggressive
Elevated furin expression in aggressive human head and neck tumors and tumor cell lines
✍ Daniel E. Bassi; Haleh Mahloogi; Luma Al-Saleem; Ricardo Lopez De Cicco; John A. πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 401 KB

Pro-protein convertases (PCs) are proteases that recognize and cleave precursor proteins. Furin, a well-studied PC, is ubiquitously expressed, and it has been implicated in many physiological and pathological processes. Some substrates for furin, such as membrane type 1 (MT1) matrix metalloproteinas

Flow cytometric evaluation of cell dispe
Flow cytometric evaluation of cell dispersion from human head and neck tumors
✍ J. Th. Bijman; D. J. Th. Wagener; H. van Rennes; J. M. C. Wessels; P. van den Br πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 688 KB

The preparation of single-cell suspensions from 25 human head and neck tumors is described. Dispersal was performed overnight at 4Β°C under slight agitation of the tissue suspensions using various combinations of enzymes and additives. The cell suspensions were examined for number of cells released,

Photodynamic effects of anthracyclin der
Photodynamic effects of anthracyclin derivatives on squamous cell carcinoma cell lines of the head and neck
✍ B.M. Lippert; A. Teymoortash; C. KΓΌlkens; B.J. Folz; J.A. Werner πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 231 KB πŸ‘ 1 views

## Abstract ## Background and Objective In the last years, photodynamic therapy, performed with hematoporphyrin derivatives, gained in importance for the treatment of superficially situated malignomas. The use of hematoporphyrin as photosensitizer is limited especially by the low depth of penetrat

Establishment of tumor cell lines from a
Establishment of tumor cell lines from a patient with head and neck cancer and their different sensitivities to anti-cancer agents
✍ Sohtaro Komiyama; Katsuko Matsui; Shohji Kudoh; Ichiro Nogae; Yuichiro Kuratomi; πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 660 KB

The authors established five cell lines from a human head and neck tumor. The five cell lines (HC-2, HC-3, HC-4, HC-7, and HC-9) exhibited different sensitivities to Adriamycin, cisplatin, bleomycin, 5- fluorouracil, vincristine, and daunomycin. The Dw was 200 ng/ml Adriamycin (doxorubicin) for HC-7