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Radiolabeling of Bombesin-Like Peptide with 99m Tc: 99m Tc-Litorin and Biodistribution in Rats †

✍ Scribed by Durkan, Kubra; Lambrecht, Fatma Yurt; Unak, Perihan


Book ID
127334537
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
181 KB
Volume
18
Category
Article
ISSN
1043-1802

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A series of salicylidene-aminoacid Schiff bases was synthesized and labeled with Tc-99m, in neutral pH, using stannous ion as reductant. Labeling yield was greatly affected by concentration-ratios of the reactants, the optimum concentration ratio being 18.5 x 1 O-2nuno1 ligand to 0.4 x 10-2mmol SnC1