A new series of diphenylpropynone (DPP) derivatives for use in vivo to image β-amyloid (Aβ) plaques in the brain of patients with Alzheimer's disease (AD) were synthesized and characterized. Binding experiments in vitro revealed high affinity for Aβ (1-42) aggregates at a K(i) value ranging from 6 t
Radiolabeled probes for imaging Alzheimer’s plaques
✍ Scribed by P.V. Kulkarni; V. Arora; A.C. Roney; C. White III; M. Bennett; P.P. Antich; F.J. Bonte
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 115 KB
- Volume
- 241
- Category
- Article
- ISSN
- 0168-583X
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