Radioimmunoscintigraphy of ovarian cancer with 131-iodine labeled OC-125 antibody fragments
โ Scribed by Georg Barzen; Anton Carl Mayr; Mathias Langer; Rolf Becker; Michael Cordes; Christian Zwicker; Klaus Koppenhagen; Roland Felix
- Book ID
- 104684103
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 649 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0340-6997
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Fifteen patients with or suspected of having ovarian carcinoma were injected intravenously (i.v.) or intraperitoneally (i.p+) with t3tl-labelled OC 125 F(ab')z. Radioimmunoscintigraphy after i.v. injection revealed 50% of the tumor sites. After i.p. injection all tumor sites were visualized, except
In 11 patients with rectal cancer, a mixture of F(ab')2 fragments of anti-carcinoembryonic antigen and anti-CA 19.9 labelled with a diagnostic dose of iodine-131 (3-10 MBq) was administered submucosally around the tumour. In this study, the local kinetics in and the dose to the rectal wall, the whol