In vitro cytotoxicity of 131I-labeled monoclonal antibody OC125 F(ab)2 on epithelial ovarian cancer cell lines
β Scribed by E.S. Gadicke; C. Lau; R. Macklis; N. Finkler; R. Knapp
- Book ID
- 119053903
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 163 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0090-8258
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3'I-labelled HMFGl or HMFGl F(ab')2 monoclonal antibody (MAb) was administered intraperitoneally to I S patients with epithelial ovarian cancer who had completed chemotherapy and were in complete or good partial remission. Each patient received 2-3 mCi. Patients were scanned immediately after and un
Ovarian cancer is a highly malignant tumor of mainly postmenopausal women. The long-term prognosis of this malignancy is largely determined by micrometastasis present at the time of second-look surgery. In general, patients face a poor outcome. New radio-immunoscintigraphic methods to target tumor t