## Introduction Guanadrel s u l f a t e (Hylorel@) (4) i s an a n t i h y p e r t e n s i v e (2-7) drug o f demonstrated c l i n i c a l u t i l i t y . We prepared r a d i o a c t i v e forms o f t h i s drug f o r \*Guanadrel s u l f a t e i s t h e USAN name f o r (~,4-dioxaspiro[4.5]dec-2-ylm
Radiogaschromatograph for carbon-14 and tritium labelled organic compounds
โ Scribed by L. Bruzzi; A. Castelli; A. Cervellati
- Publisher
- Elsevier Science
- Year
- 1964
- Weight
- 542 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0029-554X
No coin nor oath required. For personal study only.
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## Abstract Tritium labelled pentamidine has been prepared with a specific activity of 90 mCi mmol^โ1^ using a oneโstep exchange reaction between the unlabelled drug and tritiated water. The labelling utilised a homogeneous rhodium trichloride catalyst and yielded pentamidine regiospecifically labe
## Abstract Nโ[4โ]2โ(5โChloro โ2โmethoxybenzamido) ethyl phenylsulfonyl Nโฒ โcyclohexylurea, IXc, or glyburide, has been labeled with tritium and carbonโ 14. The tritium label is located in the Cโ3 position of the 5โchloro โ2โmethoxybenzoyl portion of the molecule, while the carbonโ14 label is incor
Timefurone (I), a methyl thioether analogue of khel lin (2), was labeled with tritium at the C-2 position and with carbon-14 at the C-5 position for conducting in uivo biotransformation studies with I . Tritium labeled I was prepared by lithiating and tritiating a silyllated derivative of khellinone