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Radical Route for the Alkylation of Purine Nucleosides at C6 via Minisci Reaction

โœ Scribed by Xia, Ran; Xie, Ming-Sheng; Niu, Hong-Ying; Qu, Gui-Rong; Guo, Hai-Ming


Book ID
121883805
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
587 KB
Volume
16
Category
Article
ISSN
1523-7060

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## Abstract A highly selective method for the synthesis of Nโ€9 alkylated purine nucleoside derivatives __via__ an intermolecular hydrogen abstraction reaction between nitrogen radicals in purine rings and alkyl ethers was developed. Novel purine nucleoside derivatives were obtained with good to hig