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(-)-(R)- and (+)-(S)-Carvone in the Synthesis of Optically Active Acetylenic Alcohols, Ethers, and Dichlorosilyl Derivatives.

✍ Scribed by E. A. Dikusar; N. G. Kozlov; K. L. Moiseichuk


Publisher
John Wiley and Sons
Year
2003
Weight
132 KB
Volume
34
Category
Article
ISSN
0931-7597

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Synthesis of (R)- and (S)-5-(Hydroxymeth
✍ Erwin G. J. C. Warmerdam; Johannes Brussee; Arne van der Gen; Chris G. Kruse πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 German βš– 332 KB

## Abstract The (__R__)‐ and (__S__)‐5‐(hydroxymethyl)‐3‐isopropyloxazolidin‐2‐ones, ((__R__)‐ and (__S__)‐2, resp.), pivotal intermediates in the preparation of optically active β‐blockers, were synthesized using (__R,E__)‐2‐hydroxypent‐3‐enenitrile (1) as the chiral starting material. In the synt