(R)- and (S)-5-trimethylsilyl-2-cyclohexenone: a versatile chiral source for the synthesis of optically active cyclohexanone derivatives
β Scribed by Morio Asaoka; Kunihisa Shima; Hisashi Takei
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 250 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Optically active trans-4-(tert-butyldimethylsiloxymethyl)-5-(tert-butyldimethylsiloxy)-2-cyclohexenone (2) has been synthesized in 25% overall yield starting from easily available 1,4-bis(benzyloxy)-2,3-epoxy butane (3). The enone 2 reacts with excellent stereoselectivity with RCu(CN)Li thus working
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