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Design and synthesis of a chiral hapten for a radioimmunoassay of the antidepressant (2S, 3S, 5R)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol hydrochloride

โœ Scribed by David L. Musso; James L. Kelley


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
222 KB
Volume
6
Category
Article
ISSN
0957-4166

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(R,R)-2,3-Butanediol and (s)-pinanediol
โœ Donald S. Matteson; J. Douglas Campbell ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 638 KB

R,R)-Butanediol (dichloromethy1)boronate (1) with I equiv. allylmagnesium halide yields (R,R)-2,3butanediol (1 S)-(1 -chloro-3-butenyl)boronate (3) together with the diallylated product (R,R)-2,3-butanediol(1 -allyl-3-butenyl)boronate (4). The formation of 4 is unprecedented in reactions of a-chloro