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Quantitative structure-activity relationships for the inhibition of Escherichia coli dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines

✍ Scribed by Li, Renli; Poe, Martin


Book ID
127060821
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
679 KB
Volume
31
Category
Article
ISSN
0022-2623

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Quantitative structure-activity relation
✍ Jonathan D. Hirst; Ross D. King; Michael J. E. Sternberg πŸ“‚ Article πŸ“… 1994 πŸ› Springer Netherlands 🌐 English βš– 914 KB

Neural networks and inductive logic programming (ILP) have been compared to linear regression for modelling the QSAR of the inhibition of E. coli dihydrofolate reductase (DHFR) by 2,4-diamino-5-(substituted benzyl)pyrimidines, and, in the subsequent paper [