Quantitative structure-activity relationships by neural networks and inductive logic programming. II. The inhibition of dihydrofolate reductase by triazines

Quantitative structure-activity relation

Quantitative structure-activity relationships by neural networks and inductive logic programming. I. The inhibition of dihydrofolate reductase by pyrimidines

✍ Jonathan D. Hirst; Ross D. King; Michael J. E. Sternberg 📂 Article 📅 1994 🏛 Springer Netherlands 🌐 English ⚖ 914 KB

Neural networks and inductive logic programming (ILP) have been compared to linear regression for modelling the QSAR of the inhibition of E. coli dihydrofolate reductase (DHFR) by 2,4-diamino-5-(substituted benzyl)pyrimidines, and, in the subsequent paper [