Quantitative structure-activity relationships by neural networks and inductive logic programming. I. The inhibition of dihydrofolate reductase by pyrimidines

✍ Scribed by Jonathan D. Hirst; Ross D. King; Michael J. E. Sternberg

• Publisher: Springer Netherlands
• Year: 1994
• Tongue: English
• Weight: 914 KB
• Volume: 8
• Category: Article
• ISSN: 0920-654X
• DOI: 10.1007/bf00125375

✦ Synopsis

Neural networks and inductive logic programming (ILP) have been compared to linear regression for modelling the QSAR of the inhibition of E. coli dihydrofolate reductase (DHFR) by 2,4-diamino-5-(substituted benzyl)pyrimidines, and, in the subsequent paper [