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Quantitative Structural Rearrangement of HIV-1 Reverse Transcriptase on Binding to Non-Nucleoside Inhibitors

✍ Scribed by Luckhana Lawtrakul; Anton Beyer; Supa Hannongbua; Peter Wolschann

Publisher
Springer Vienna
Year
2004
Tongue
English
Weight
322 KB
Volume
135
Category
Article
ISSN
0026-9247

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## Abstract An extended spectrum of HIV‐1 reverse‐transcriptase (RT) mutations in HAART‐treated patients has been recently described. To verify the possible association of previously unreported RT mutations with a decrease of phenotypic susceptibility to nucleoside (NRTIs) and non‐nucleoside (NNRTI