𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lead Optimization of Diarylpyrimidines as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase

✍ Scribed by Zhao-Sen Zeng; Yong-Hong Liang; Xiao-Qing Feng; Fen-Er Chen; Christophe Pannecouque; Jan Balzarini; Erik De Clercq

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
369 KB
Volume
5
Category
Article
ISSN
1860-7179

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design, Synthesis, and SAR of Naphthyl-S
Design, Synthesis, and SAR of Naphthyl-Substituted Diarylpyrimidines as Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase
✍ Yong-Hong Liang; Xiao-Qing Feng; Zhao-Sen Zeng; Fen-Er Chen; Jan Balzarini; Chri 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 314 KB 👁 1 views

## Abstract __A series of 38 2‐naphthyl‐substituted diarylpyrimidine (DAPY) analogues, characterized by various substitution patterns on the pyrimidine and naphthalene rings, was synthesized in a straightforward fashion by means of parallel synthesis and evaluated as inhibitors of the HIV‐1 wild‐ty