✦ LIBER ✦

Quantitative measurement of autoantibodies to recombinant mitochondrial antigens in patients with primary biliary cirrhosis: Relationship of levels of autoantibodies to disease progression

✍ Scribed by MD Van Norstrand; M Malinchoc; KD Lindor; TM Therneau; ME Gershwin; PS Leung; ER Dickson; HA Homburger

Book ID: 118686522
Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 215 KB
Volume: 25
Category: Article
ISSN: 0270-9139
DOI: 10.1053/jhep.1997.v25.pm0008985257

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Quantitative measurement of autoantibodi

Quantitative measurement of autoantibodies to recombinant mitochondrial antigens in patients with primary biliary cirrhosis: Relationship of levels of autoantibodies to disease progression

✍ Michael D. Van Norstrand; Michael Malinchoc; K. D. Lindor; T. M. Therneau; M. E. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

## AMAs are detectable by indirect immunofluorescence (IF) We examined the clinical usefulness of measurements on tissue substrates in 93% to 99% of patients with PBC, but of antimitochondrial autoantibodies (AMA) in prethis method also detects AMAs of differing specificities in dicting disease pr

Autoantibody IgG subclasses to recombina

Autoantibody IgG subclasses to recombinant antigens and the role of bacterial stimuli in primary biliary cirrhosis

✍ Toshihiro Kawai; Naomi Hosoya; Yuki Moritoki; Yusuke Kajiyama; Masashi Watanabe; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

The predominance of IgG3 and IgM isotype

The predominance of IgG3 and IgM isotype antimitochondrial autoantibodies against recombinant fused mitochondrial polypeptide in patients with primary biliary cirrhosis

✍ Charles D. Surh; Anne E. Cooper; Ross L. Coppel; Patrick Leung; Aftab Ahmed; Rol 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 684 KB

Autoantibodies against inner mitochondrial membrane proteins are a hallmark of primary biliary cirrhosis. Specifically, these antimitochondrial autoantibodies recognize two polypeptides of approximately 70 and 52 kD, respectively. Although the specificity of antimitochondrial autoantibodies has been

Synthesis of interleukin-1β in primary b

Synthesis of interleukin-1β in primary biliary cirrhosis: Relationship to treatment with methotrexate or colchicine and disease progression

✍ Laurie C. Miller; Dr Archna Sharma; Augusta F. McKusick; Dr Joseph P. Tassoni; C 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 702 KB

Primary biliary cirrhosis (PBC) is a chronic, progressive, cholestatic liver disease. Interleukin-lp (JL-lp) may play a role in the pathogenesis of PBC by contributing to altered immune function and fibrosis. Colchicine or methotrexate has some beneficial effects in the treatment of PBC, and also af

The in vitro production of antibodies to

The in vitro production of antibodies to mitochondrial antigens by peripheral blood mononuclear cells from patients with primary biliary cirrhosis

✍ Mark I. Avigan; Gregory Adamson; Jay H. Hoofnagle; E. Anthony Jones 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 684 KB

Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non

Decrease of hepatic triglyceride lipase

Decrease of hepatic triglyceride lipase levels and increase of cholesteryl ester transfer protein levels in patients with primary biliary cirrhosis: Relationship to abnormalities in high-density lipoprotein

✍ Dr. Hisatoyo Hiraoka; Shizuya Yamashita; Yuji Matsuzawa; Masaharu Kubo; Shuichi 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 937 KB

Serum levels of high-density lipoprotein cholesterol are often increased in patients with primary biliary cirrhosis. To elucidate the mechanism of the elevation of high-density lipoprotein cholesterol levels in this disease, lipoprotein abnormalities were analyzed in 10 patients subdivided into two