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Quantitative extraction of methylmalonic and succinic acids and their determination by gas-liquid chromatography

โœ Scribed by C.V. Warner; George V. Vahouny


Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
493 KB
Volume
67
Category
Article
ISSN
0003-2697

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โœฆ Synopsis


A method for routine small-volume solvent extraction, derivitization and gasliquid chromatographic analysis of methylmalonic and succinic acids is described. The procedure allows for quantitative determination of mass and radioactivity of these acids and can be applied to metabolic studies of the genetic disorder methylmalonylacidurea.


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