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Quantitative assessment of the binding of acetaminophen metabolites to mouse liver microsomal phospholipid

✍ Scribed by Albrecht Wendel; Jurgen Hallbach

Book ID
115778869
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
600 KB
Volume
35
Category
Article
ISSN
0006-2952

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✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy