Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry
✍ Scribed by Mangerich, Aswin; Veith, Sebastian; Popp, Oliver; Fahrer, Jörg; Martello, Rita; Bohr, Vilhelm A.; Bürkle, Alexander
- Book ID
- 119321139
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 310 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0047-6374
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Serum theophylline analysis was attempted using stable isotope dilution mass spectrometry. Theophylline "Nlabelled in position 7 was used as internal standard. The analysis was performed at resolution 3OOO by selected ion monitoring with temperature programming. The sample was introduced in underiva
8-[4,5,6,8- \(\left.{ }^{13} \mathrm{C}_{4}\right]\) Hydroxyguanine and \(\left[4,5,6-{ }^{13} \mathrm{C}_{3}\right]\) guanine were prepared by total synthesis. The labeled compounds were used as internal standards in a gasliquid chromatographic-mass spectrometric method for quantitative determinati
Tandem mass spectrometry (MS/MS) has the significant advantage of improving selectivity and overcoming interferences present in conventional mass spectrometry. The quantitative use of MS/MS is discussed with reference to sources of instrumental error and ways to minimize such errors. Key parameters