Quantitative analysis of survivin in colorectal adenocarcinoma: increased expression and correlation with telomerase activity
โ Scribed by Alfred King-Yin Lam; Said Saleh; Robert Anthony Smith; Yik-Hong Ho
- Book ID
- 116534501
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 186 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1532-8392
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The human telomerase enzyme is composed of two essential components, hTR, which acts as a template for reverse transcription, and hTERT, which is the putative catalytic subunit for the enzyme. Recent studies have demonstrated a good correlation between hTERT expression and telomerase activation, whe
Tissues and sera from 110 patients diagnosed with colorectal primary carcinoma, 20 patients with benign colorectal diseases and 31 healthy donors were subjected to quantitative CEA analysis. Multiple samples from tumor lesions and autologous histologically normal mucosa (10 cm from the tumor) were o