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Quantitative Analysis of Telomerase hTERT mRNA and Telomerase Activity in Endometrioid Adenocarcinoma and in Normal Endometrium

โœ Scribed by Rainer Lehner; Takayuki Enomoto; James A. McGregor; A.Laurie Shroyer; Bryan R. Haugen; Umarani Pugazhenthi; Kenneth R. Shroyer

Book ID
112248759
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
163 KB
Volume
84
Category
Article
ISSN
0090-8258

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Telomerase extends telomeric repeats at the ends of linear chromosomes, thereby prolonging the replicative capacity of cells. To investigate possible regulatory mechanisms of telomerase, we measured telomerase enzyme activity, human telomerase RNA (hTR) and human telomerase reverse transcriptase (hT