The human telomerase enzyme is composed of two essential components, hTR, which acts as a template for reverse transcription, and hTERT, which is the putative catalytic subunit for the enzyme. Recent studies have demonstrated a good correlation between hTERT expression and telomerase activation, whe
Telomerase activity in colorectal carcinoma and its correlation with expression of c-myc
โ Scribed by Jian-Lun Liu; Lian-ying Ge; Gui-nian Zhang
- Publisher
- Chinese Anti-Cancer Association
- Year
- 2005
- Tongue
- English
- Weight
- 361 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1000-9604
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## Background and objectives: Telomerase is thought to be responsible for cell immortality, and bcl-2 has been demonstrated to regulate apoptosis. recent studies have shown a wide occurrence of telomerase activation and bcl-2 deregulation in human carcinoma cells. ## Methods: We examined telomera