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Quantitative analysis of hTERT mRNA expression in colorectal cancer

✍ Scribed by Hideaki Niiyama; Kazuhiro Mizumoto; Norihiro Sato; Eishi Nagai; Ryuichi Mibu; Takafumi Fukui; Moritoshi Kinoshita; Masao Tanaka

Book ID: 119390580
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 120 KB
Volume: 96
Category: Article
ISSN: 0002-9270
DOI: 10.1016/s0002-9270(01)02453-4

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## Abstract In a majority of malignant human tumors telomerase activity can be detected, suggesting an immortal phenotype. Expression of the reverse transcriptase subunit, hTERT, in the human telomerase complex is required for telomerase activity. The regulation of hTERT, from gene level to a fully