A method for the determination of doxorubicin and daunorubicin in plasma is described. The plasma is injected directly into a loop column and then washed with water. After switching the injection valve, the sample is separated on a phenyl column using detection at 254 nm. The detection limit is 10 n
Quantification of midodrine and its active metabolite in plasma using a high performance liquid chromatography column switching technique
β Scribed by Werner Posch; Wolfgang Lindner
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 384 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0269-3879
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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The cleanβup and separation of the samp