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Quality of life after free-flap reconstruction in patients with oral and pharyngeal cancer

✍ Scribed by Mari Markkanen-Leppänen; Antti A. Mäkitie; Marja-Leena Haapanen; Erkki Suominen; Sirpa Asko-Seljavaara

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
90 KB
Volume
28
Category
Article
ISSN
1043-3074

No coin nor oath required. For personal study only.

✦ Synopsis

Background:

Our aim was to investigate quality of life and outcome after microvascular free-flap reconstruction after oncologic surgery.

Methods:

Forty-four patients with a large carcinoma in the oral cavity, oral pharynx, or hypopharynx underwent free-flap surgery with or without radiotherapy. patients completed the university of washington quality-of-life questionnaire preoperatively and four times during the 12 postoperative months. survival rates and complications were analyzed.

Results:

Postoperative composite quality-of-life scores were significantly lower than before treatment with no significant overall improvement during the follow-up. the scores for disfigurement, chewing, speech, and shoulder function remained significantly below the preoperative level throughout the follow-up. sociodemographic factors predicted quality of life. heavy drinking and unemployment caused a 2.4-fold and a 4.4-fold increase in risk of death, respectively. the rates for overall survival, tumor recurrence, flap success, and surgical complications were consistent with previous literature.

Conclusion:

Sociodemographic variables affect quality of life and patient survival in patients with oral cancer treated with microvascular free-flap reconstruction.

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