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Malnutrition and quality of life in patients treated for oral or oropharyngeal cancer

✍ Scribed by Harriët Jager-Wittenaar; Pieter U. Dijkstra; Arjan Vissink; Bernard F. A. M. van der Laan; Rob P. van Oort; Jan L. N. Roodenburg

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
110 KB
Volume
33
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background.

This study assessed whether malnourished patients score lower on quality of life after treatment for oral/oropharyngeal cancer.

Methods.

Malnutrition (weight loss ≥10% in 6 months/≥5% in 1 month) and quality of life (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 questionnaire) were assessed cross‐sectionally in patients treated for oral/oropharyngeal cancer. The interval after treatment varied from 1 day to 3 years. The relationship between malnutrition and quality of life was analyzed univariately (Mann–Whitney U test) and multivariately (linear regression analyses). Statistical significance was set at p < .05.

Results.

Prevalence of posttreatment malnutrition was 16% (18/115, 95% confidence interval [CI]: 9% to 23%). Analyzed univariately, malnourished patients scored significantly worse on physical functioning (p = .007) and fatigue (p = .034) than well‐nourished patients. Multivariate analysis revealed that malnutrition was significantly related to physical functioning (p = .015).

Conclusions.

Malnourished patients treated for oral/oropharyngeal cancer score lower on quality of life scales related to physical fitness. © 2010 Wiley Periodicals, Inc. Head Neck, 2011

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