In clinical studies, we often consider not only patients' survival time, but also their quality of life. Quality adjusted life years (QALY) is an integrated measure of medical outcome that combines a patient's quantity and quality of life. Estimation of mean QALY for a group of patients is complicat
Quality-Adjusted Survival Estimation with Periodic Observations
โ Scribed by Pai-Lien Chen; Pranab K. Sen
- Book ID
- 110724948
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 673 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0006-341X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
To compare both mortality and quality of life (QOL) across different illnesses, we propose an estimator to calculate the expected quality adjusted survival (QAS) by multiplying the QOL into the survival function. While the survival function can be determined by the usual life table method, the QOL d
One way of examining trade-offs between quantity and quality of life (QOL) is to combine them into a single measure such as quality-adjusted life year (QALY). If censoring occurs, then estimation presents some difficulties. One approach, known as Q-TWiST, is to define a series of health states, use
The expected quality-adjusted survival (QAS) for an index population with a speci"c disease can be estimated by summing the product of the survival function and the mean quality of life function of the population. In many follow-up studies with heavy censoring, the expected QAS may not be well estim