To compare both mortality and quality of life (QOL) across different illnesses, we propose an estimator to calculate the expected quality adjusted survival (QAS) by multiplying the QOL into the survival function. While the survival function can be determined by the usual life table method, the QOL d
Expressing Estimators of Expected Quality Adjusted Survival as Functions of Nelson-Aalen Estimators
โ Scribed by Yijian Huang; Thomas A. Louis
- Book ID
- 110278062
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 115 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1380-7870
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๐ SIMILAR VOLUMES
In clinical studies, we often consider not only patients' survival time, but also their quality of life. Quality adjusted life years (QALY) is an integrated measure of medical outcome that combines a patient's quantity and quality of life. Estimation of mean QALY for a group of patients is complicat
The expected quality-adjusted survival (QAS) for an index population with a speci"c disease can be estimated by summing the product of the survival function and the mean quality of life function of the population. In many follow-up studies with heavy censoring, the expected QAS may not be well estim