In clinical studies, we often consider not only patients' survival time, but also their quality of life. Quality adjusted life years (QALY) is an integrated measure of medical outcome that combines a patient's quantity and quality of life. Estimation of mean QALY for a group of patients is complicat
Efficient Estimation of the Distribution of Quality-Adjusted Survival Time
โ Scribed by Hongwei Zhao; Anastasios A. Tsiatis
- Book ID
- 110724639
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 579 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0006-341X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
To compare both mortality and quality of life (QOL) across different illnesses, we propose an estimator to calculate the expected quality adjusted survival (QAS) by multiplying the QOL into the survival function. While the survival function can be determined by the usual life table method, the QOL d
The expected quality-adjusted survival (QAS) for an index population with a speci"c disease can be estimated by summing the product of the survival function and the mean quality of life function of the population. In many follow-up studies with heavy censoring, the expected QAS may not be well estim