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Pyrrolo[2,1-c][1,4]benzodiazepines : A mild conversion of thiolactam into amidine.

✍ Scribed by Mari P. Foloppe; Sylvain Rault; Max Robba

Book ID
108380315
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
144 KB
Volume
33
Category
Article
ISSN
0040-4039

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## 12 -132 2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines. -Benzodiazepinone derivatives (I) are transformed into the corresponding thiolactams (II), which can be converted to a new series of diversely substituted amidines [cf. (IV), (V)]. Ammonia, primary amines and h