ChemInform Abstract: 2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines.
β Scribed by B. PUODZIUNAITE; L. KOSYCHOVA; R. JANCIENE; Z. STUMBREVICIUTE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
12 -132
2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines.
-Benzodiazepinone derivatives (I) are transformed into the corresponding thiolactams (II), which can be converted to a new series of diversely substituted amidines [cf. (IV), (V)]. Ammonia, primary amines and hydrazine give good yields, while secondary amines give low yields only. -(
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