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ChemInform Abstract: 2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines.

✍ Scribed by B. PUODZIUNAITE; L. KOSYCHOVA; R. JANCIENE; Z. STUMBREVICIUTE


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


12 -132

2,3-Dihydro-1H-1,5-benzodiazepines: A Conversion of Thiolactams to Amidines.

-Benzodiazepinone derivatives (I) are transformed into the corresponding thiolactams (II), which can be converted to a new series of diversely substituted amidines [cf. (IV), (V)]. Ammonia, primary amines and hydrazine give good yields, while secondary amines give low yields only. -(


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