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ChemInform Abstract: 1,2,3-Triazolo[1,5-a][1,4]- and 1,2,3-Triazolo[1,5-a][1,5]benzodiazepine Derivatives: Synthesis and Benzodiazepine Receptor Binding.

✍ Scribed by L. BERTELLI; G. BIAGI; I. GIORGI; O. LIVI; C. MANERA; V. SCARTONI; C. MARTINI; G. GIANNACCINI; L. TRINCAVELLI; P. L. BARILI

Publisher: John Wiley and Sons
Year: 2010
Weight: 37 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199841161

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With sodium borohydride in tetrahydrofuran/ethanol (5 : 1). the product ( I ) gives a 75 yield of a compound, m.p. 233 "C, that is identical with the recently prepared 2-(diphenylmethyl)imidaz0le[~1. When product ( I ) is boiled for 2 h in tetrahydrofuran/water (2: I ) it affords 2-(hydroxy-dipheny