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Pyrrolo[1,2-a]indole chemistry. Reactions of a tridentate carbanion

โœ Scribed by Franck, Richard W.; Bernady, Karel F.


Book ID
126325023
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
876 KB
Volume
33
Category
Article
ISSN
0022-3263

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9H-Pyrrolo[1,2-a]indoles
โœ Mazzola, Vincent J.; Bernady, Karel F.; Franck, Richard W. ๐Ÿ“‚ Article ๐Ÿ“… 1967 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 576 KB
Synthetic studies on substituted 9h-pyrr
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## Mitomycin antibiotics (I) have a novel ring system that is aziridinopyrrolo II 1,2-a indoloquinone(1). In synthetic studies on mitomycin analogs Lederle group synthesised 7-benzyloxy-9H-pyrrolo 1,2-a indole(2) and substituted 2,3r.

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Considerable attention has been given during the last decade to some metabolic products of a group of Streptomyces, "the mitomycines", which show remarkable antibiotic and antitumoral activity.