Pyrrolo[1,2-a][1,4]benzodiazepine: A Novel Class of Non-azole anti-Dermatophyte Antifungal Agents.
β Scribed by Lieven Meerpoel; Jef Van Gestel; Frans Van Gerven; Filip Woestenborghs; Patrick Marichal; Vic Sipido; Gilkerson Terence; Roger Nash; David Corens; Ray D. Richards
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 12 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
## Abstract Heating of hexahydroβ5__H__βpyrrolo[2,1β__c__][1,4]benzodiazepineβ2,5,11βtrione in boiling phosphoryl chloride led to a rearranged product like 3,5βdichlorobenzo[__h__][1,6]naphthyridine. This structure was established from Xβray diffraction analysis.
## Abstract Starting from the known epoxy alcohol (I), a new strategy for the synthesis of the potent fungicide (IX) in multigram quantities is developed.