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Pyrimido[5,4-b]benzofuran and pyrimido[5,4-b]benzothiophene derivatives Ligands for α1-and 5HT1A-receptors

✍ Scribed by G Romeo; G Ambrosini; S Guccione; A De Blasi; F Russo

Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
577 KB
Volume
28
Category
Article
ISSN
0223-5234

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Synthesis of substituted pyrimido[4,5-b]
Synthesis of substituted pyrimido[4,5-b] and [5,4-c]-[1,8]naphthyridines
✍ Christophe Plisson; Jacques Chenault 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 56 KB

## Abstract Ethyl 1‐ethyl‐7‐methyl‐4‐oxo‐1,4‐dihydro[1,8]naphthyridine‐3‐carboxylate (**1**), precursor of nalidixic acid, has been converted in two steps through ([1,8]naphthyridin‐3‐yl)carbonylguanidine derivatives into substituted pyrimido[4,5‐__b__] and [5,4‐__c__][1,8]naphthyridines.