## Abstract Fused tricyclic 7‐phenyl‐5__H__‐thizolo[5,4‐__e__]pyrrolo[1,2‐__a__][1,4]diazepin‐10(9__H__)one (**10**) was prepared by thermolysis of 2‐phenyl‐4‐(1‐pyrrolylmethyl)thiazole‐5‐carbonyl azide (**9**) in acetic acid. In addition, starting from **10**, 7‐phenyl‐5__H__‐thiazolo [5,4‐__e__][
Pyrimido[4,5-e][1,4] diazepin-5-ones and 4,4-ethylenediaminobis(2-phenyl-pyrimidine-5-carboxylic acid) diethyl esters
✍ Scribed by Kim, Dong Han; Santilli, Arthur A.
- Book ID
- 121382084
- Publisher
- American Chemical Society
- Year
- 1969
- Tongue
- English
- Weight
- 234 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
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## Abstract magnified image Novel 11‐amino‐6‐aryl‐6,7‐dihydroindeno[1,2‐__e__] pyrimido[4,5‐__b__][1,4]diazepin‐5(5a__H__)‐ones 4a‐f were prepared regioselectively by the tricomponent reaction of 4,5,6‐triaminopyrimidine 1, 1,3‐indandione 2 and aromatic aldehydes 3a‐f. The bicomponent approach, us
## Abstract A new method was developed for the synthesis of 6,7‐dihydro‐5__H__‐pyrimido[4,5‐__e__][1,4]diazepin‐8(9__H__)‐one derivatives. The key to construct the pyrimido[4,5‐__e__][1,4]diazepine core is the intramolecular amidation of __N__‐((4‐amino‐6‐chloropyrimidin‐5‐yl)methyl)‐substituted am