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Pyridine isosteres of the .beta.-adrenergic antagonists, 2-(p-nitrophenyl)-1-isopropylamino-2-ethanol and 3-(p-nitrophenoxy)-1-isopropylamino-2-propanol

✍ Scribed by Gneuwuch, C. Thomas; Friedman, Harris L.


Book ID
120430079
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
485 KB
Volume
15
Category
Article
ISSN
0022-2623

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✍ A. Bobik; E. A. Woodcock; C. I. Johnston; W. J. Funder πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 French βš– 250 KB

## Abstract The preparation of an iodine‐125 labelled beta adrenergic ligand, 3–(4‐iodophenoxy)‐1‐isopropylamino‐2‐propanol, suitable for β‐adrenergic receptor membrane binding studies is described. Several preparations have been carried out with radiochemical yields of 20–30%. Specific activities