✦ LIBER ✦

The preparation and purification of 3–(4-iodophenoxy)-1-isopropylamino-2-propanol-125I, a beta adrenergic antagonist

✍ Scribed by A. Bobik; E. A. Woodcock; C. I. Johnston; W. J. Funder

Publisher: John Wiley and Sons
Year: 1977
Tongue: French
Weight: 250 KB
Volume: 13
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580130419

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The preparation of an iodine‐125 labelled beta adrenergic ligand, 3–(4‐iodophenoxy)‐1‐isopropylamino‐2‐propanol, suitable for β‐adrenergic receptor membrane binding studies is described. Several preparations have been carried out with radiochemical yields of 20–30%. Specific activities in the order of 150 Ci/mmol are readily obtained.

📜 SIMILAR VOLUMES

The preparation and purification of labe

The preparation and purification of labelled β-adrenergic blocking agents. Part I. Synthesis of carbon-14 and tritium labelled 1-isopropylamino-3-(1-naphthyloxy)-propan-2-ol hydrochloride, (propranolol hydrochloride, inderal

✍ J. Burns 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 444 KB 👁 1 views

The preparation of 1"-propranolol hydrochloride from l-naphthol-I-14C is described. Several preparations of the compound have been carried out with overall radiochemical yields of 17 %-21 %. Specific activities of 3.51 pCilmg, 8.8 pCilmg, and 23.2 pCilmg have been obtained. Propranolol has also bee

ChemInform Abstract: (3R,4S)-3-[4-(4-Flu

ChemInform Abstract: (3R,4S)-3-[4-(4-Fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: A Conformationally Restricted Analogue of the NR2B Subtype-Selective NMDA Antagonist (1S,2S)-1-(4-Hydroxyphenyl)-2- (4-hydroxy-4-phenylpiperidino)-1-propanol.

✍ B. L. CHENARD; ET AL. ET AL. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Preparation and properties of (R)-(−)-1-

Preparation and properties of (R)-(−)-1-azabicyclo[2.2.2]oct-3-yl-(R)-(+)-α-hydroxy-α-(4-[125I]iodophenyl)-a-phenyl Acetate and (R)-(−)-1-Azabicyclo[2.2.2]oct-3-yl-(S)-(−)-α-hydroxy-α-(4-[125I]iodophenyl)-α-phenyl acetate as potential radiopharmaceuticals

✍ Victor I. Cohien; Waclaw J. Rzeszotarski; Raymond E. Gibson; Linda H. Fan; Richa 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 479 KB

The pharmacologic Actions of the Broncxh

The pharmacologic Actions of the Broncxhodilator Drug, Isoetharine * 1 *Pharmacology section, Sterling-Winthrop Research Institute, Rensselaer, N. Y. 1Isoetharine is 1- (3,4-dihydroxyphenyl)~2-isopropylamino-I-hutanol hydrochloride. It is identified commercially by the name Dilabron, a registered trademark of Oeo. A. Breon and Co

✍ Lands, A.M. ;Luduena, F.P. ;Hoppe, J.O. ;Oyen, Irene H. 📂 Article 📅 1958 🏛 Elsevier ⚖ 472 KB

ChemInform Abstract: Preparation of Opti

ChemInform Abstract: Preparation of Optically Active Azophenolic Crown Ethers Containing 1-Phenylethane-1,2-diol and 2,4-Dimethyl-3-oxapentane-1,5-diol as a Chiral Subunit (I)—(IV): Temperature-Dependent Enantiomer Selectivity in the Complexation with Chiral Amines.

✍ K. OGASAHARA; K. HIROSE; Y. TOBE; K. NAEMURA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 3 views