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Pyridindene Derivatives. III. Synthesis from Arecoline

โœ Scribed by PLATI, JOHN T.; INGBERMAN, ARTHUR K.; WENNER, WILHELM


Book ID
126184130
Publisher
American Chemical Society
Year
1957
Tongue
English
Weight
699 KB
Volume
22
Category
Article
ISSN
0022-3263

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Peptides from non-amino acid sources III
โœ G.J. Koves; I.G. Csizmadia ๐Ÿ“‚ Article ๐Ÿ“… 1971 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 192 KB

We wish to report a new synthetic route to N,N'-disuhstituted diketopiperazines (VI) via their tetraethyl acetals (V) from ketene acetal (I) and sulfonic azides (II). Compounds I and II reacted completely within 24 hours at -20ยฐC in a 1:l molar ratio in the absence of a solvent. The yield was nearl