Synthesis of Benzoxazepine Derivatives III. Isoindolinones
✍ Scribed by Jacques Pecher; Adolphe Waefelaer; Paul Poultier
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 193 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0037-9646
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📜 SIMILAR VOLUMES
## Abstract A simple approach to the fluorinated 1,5‐benzoxazepine ring system is described. By reacting commercially accessible aminophenols 1 and the trifluoroacetylvinyl ether 2, high yields of enaminones 3 were obtained. Functionalization of methyl group of compounds 3 gave rise to dieneamines
## Abstract A new series of 4‐(4‐methylpiperazin‐1‐yl)thieno[2,3‐__b__][1,5]benzoxazepines **1a‐k** has been synthesized from 4‐bromo‐2‐methylthiophene **6** or ethyl 2‐amino‐4,5‐dimethyl‐3‐thiophencarboxylate **10**. Preparation of the key intermediate thieno[2,3‐__b__][1,5]benzoxazepine‐4(5__H__)
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